• Bromidrosis is foot odor caused when normally odorless sweat becomes overgrown with bacteria that break down perspiration into strong‑smelling acids. Hyperhidrosis—excessive sweating of the feet—creates the moist environment that allows these bacteria to thrive.
• Foot odor is produced by multiple skin bacteria, including those that generate isobutyric acid (“dirty sock” smell) and isovaleric acid (“smelly feet” odor). Athlete’s foot increases bacterial load and often worsens odor.
• Hyperhidrosis affects the soles due to their high concentration of sweat glands. It may be idiopathic (overactive sweat glands triggered by stress or sympathetic nerve activity) or secondary to conditions such as diabetes, hyperthyroidism, or neurological disorders.
• Excessive sweating appears as cool, moist, pink skin with maceration between the toes. Shoes often become damp or moldy, creating an ideal environment for bacterial and fungal overgrowth and worsening odor.
• Management focuses on reducing perspiration and lowering bacterial and fungal counts. Helpful measures include daily foot washing, rotating shoes to allow drying, wearing absorbent cotton or silver‑infused socks, using antiperspirants or drying lotions, and applying antibacterial/antifungal soaps. Severe cases may benefit from Botox injections or, rarely, surgical sympathectomy.
Bromidrosis is the medical term for foot odor which is a foul smelling perspiration. This occurs when normally odorless foot perspiration becomes overgrown with decomposing bacteria, thus producing a pungent biochemical waste.
No one bacterial species is responsible for the odor with many of the resident (normally occurring on the skin) bacteria capable of producing volatile acids. Isobutyric acid produces a “dirty sock” odor while isovaleric acid produces the “smelly feet” odor. It has been found that athletes foot actually increases the bacteria count and thus worsen the foot odor.
Hyperhidrosis It is estimated that each foot contains over 250,000 sweat glands making the feet the highest concentration for this type of gland. It is this excessive perspiration that leads to foot odor. Excessive perspiration is known as hyperhidrosis. Excessive perspiration of the soles and usually the palms as well affects about one quarter of one percent of the population.
The more common type of hyperhidrosis is idiopathic (unknown origin) which is usually from excessive stimulation of the eccrine or sweat glands. This is a sympathetic nerve response along the lines of “fight or flight”, seen in nervous individuals, again leading to foot odor.
The other type of hyperhidrosis is the pathologic form, which may be the result of diabetes, hyperthyroidism, or even a lesion of the central or peripheral nervous system.
Hyperhidrosis clinically appears as pink moist skin that is cool to touch. The foot is also clammy. Excessive perspiration between the toes results in maceration. Sometimes the hyperhidrosis can be so severe that drops of sweat actually run off the foot; I have seen this a number of times over the years. Along with this the shoes are usually damp, and moldy. It is this type of environment that leads to foot odor.
Management of both foot odor and perspiration go hand in hand. The easiest way to reduce odor is to reduce perspiration.
There are things to do to reduce the odor if you are having difficulty reducing the perspiration. Reducing foot odor tips include:
The next thing is to reduce the amount of perspiration. Reducing perspiration tips include:
Additionally, people with a severe case of hyperhidrosis can be affected psychologically. They are essentially embarrassed to be in any situation where they might have to take off their shoes and socks.
A mistake many people make is that they come home, take off their sweaty shoes and throw them into the dark, cool closet. Bacteria and fungus thrive in dark moist environments. The inside of the shoe never has a chance to dry out and the following morning is put back on the foot, further aggravating foot odor. A better idea is to leave the shoe by an open window or on a door stoop in order for the inside of the shoe to fully dry out.
Look for socks which are impregnated with silver as silver has antibacterial properties. If it is possible, changing your socks midday is also recommended.
Believe it or not but there are topical antiperspirants for the feet. Ostiderm Roll-On is one such product. This product is applied twice a day for a week, then once daily and then perhaps every couple of days to keep the feet dry.
Depending on how much your feet perspire you may have to experiment with the medication to find a regimen works best for you. Be careful not to over use the product as it will over dry your skin which should also be avoided.
Botox In recent years Botox (botulinum toxin type A) injections have become popular in diminishing perspiration in the feet and hands. The success rate is extremely high but there are a few potential adverse reactions including pain on injection, bruising, with muscle weakness being the main adverse reaction as a reaction to nerve blocks.
Since the treatment involves multiple injections with each injection occurring less than an inch apart, the total amount of injections will ultimately be determined by the size of the foot, thus it is best to have these injections done under anesthesia either intravenous sedation or via local anesthesia around the ankle which will completely numb the bottom of the foot. Each injection is limited to just underneath the skin. If the injections are done too deeply it can cause muscle weakness on the bottom of the foot.
There are contraindications for this type of treatment which include people with peripheral neuro-muscular disease, those with a hypersenitivity to Botox and women who are pregnant.
Once the perspiration is under control the next step is to reduce the bacterial and fungal population of the feet. This is accomplished by using a topical soap that has both anti-bacterial and anti-fungal properties.
Other outside factors tend to promote foot perspiration. Caffeine in coffee, tea and soda stimulates the sympathetic nervous system and thus produces more perspiration. Additionally, many patients are just anxious, nervous individuals causing excessive perspiration. Along with oral medication as mentioned earlier, stress reduction and relaxation techniques may be helpful.
Reserved for severe cases of hyperhidrosis, a procedure known as endoscopic lumbar sympathectomy (ELS) has been developed. This is a procedure where the nerves in the lumbar region of the back, specifically L-3 or L-4, are clamped off thus reducing nerve stimulation to the sweat glands on the bottom of the feet. This is a very specialized procedure which should only be performed by an experienced surgeon. It can be done on an out-patient basis.
In a study over a four year period, 154 patients underwent ELS for hyperhidrosis of the feet. Of that group 97.4% reported improvement labeled as a "cure". Complications included having to convert to an open procedure, neuralgia (inflammation of the affected nerves), temporary recurrence of foot sweating, revision and reversal of surgery.1
Warts also have a tendency to spread more rapidly in excessively moist skin.
1 Severe Plantar Hyperhidrosis: an Effective Surgical Solution
Reisfeld R, Paternack GA, Daniels PD, Basseri E, Nishi GK, Berliner KI (The Center for Hyperhidrosis, Los Angeles, CA: Private Practice, Los Angeles< CA; Private Practice, Beverly Hills, CA; Marina del Ray, CA)
Am Surg. 2013 Aug;79(8):845-853
REFERENCES
American Academy of Dermatology
ONOX-foot solution spray-once daily spray, after shower, keeps feet dry and reduces odor. Particularly effective for those with habitual fungus and those with resistant warts. (available from a third party)
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DISCLAIMER: The purpose of this site is purely informational in nature. It is not intended to diagnose, treat or cure any medical condition. This information is not a substitute for advice from a medical professional. Please consult your healthcare provider for accurate diagnosis and treatment. The information presented here may be subject to errors and omissions.
SITE LAST UPDATED: MAY 2026


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