porokeratosis

Quick Summary

Porokeratosis refers to small, seed‑like keratotic lesions on the bottom of the foot that often feel like “walking on a pebble.” They typically appear in clusters on weight‑bearing areas such as the ball of the foot or heel and can range from mildly annoying to quite painful.

These lesions are sometimes called “seed corns,” but unlike calluses or intractable plantar keratomas, they are not caused by bony pressure. They are thought to represent plugged sweat glands, though the exact cause is still debated. Because the foot contains up to 250,000 sweat glands, it is easy to see how friction and pressure can lead to clogging and formation of these tiny keratotic plugs.

Porokeratoses are benign, but any unusual or persistent growth should be examined to rule out other conditions. Pain varies depending on the number of lesions, their location, shoe type, walking habits, and the amount of natural fat padding under the foot.

Treatment ranges from simple debridement to more involved therapies. Most podiatrists begin by curetting (carving out) the lesion, which often provides immediate relief. Additional options include cushioned insoles, keratolytic agents such as salicylic acid, or sclerosing injections like 4% denatured alcohol when symptoms recur. Surgical excision is rarely recommended because scarring on the bottom of the foot can become more painful than the original lesion.

⚠️ Any persistent or worsening foot lesion should be evaluated to confirm the diagnosis and rule out more serious conditions.
Author: Dr. Marc Mitnick
Reviewed by: Medical Review Board



WHAT IS A POROKERATOSIS



Many people suffer from painful growths on the bottom of their feet. The origins of these growths are varied. The most common growth on the bottom of the foot that may be painful is known as a callus, which is a broad layer of hard skin similar in appearance to the calluses one develops on their hands after doing labor like raking leaves.

However, some people develop small hard growths usually more than one on the bottom of their feet, many will complain they feel like they have a stone in their shoe. Although there are potentially many origins of this type of lesion including warts and intractable plantar keratoma, a very common cause of this type of growth is known as a porokeratosis.

Porokeratosis is a general term to a group of dermatological problems that occur in various parts of the body.

This discussion is limited to punctate porokeratosis. These lesions are described as dozens of discrete or grouped seed-like hyperkeratotic lesions with characteristic thin, raised ridge-like margins that develop on the palms and the soles. Patients usually have other forms of porokeratosis as well, most commonly the linear or Mibelli types. Because of their description many patients will refer to them as seed corns.

These lesions generally occur on the weight bearing part of the foot which is the ball of the foot and the heel but may also occur in the mid arch. These lesions are generally not associated with any bony prominence as is the case with a callus or an intractable plantar keratoma.

plugged_sweat_gland

These lesions are thought to be nothing more than plugged sweat glands however there is some debate as to whether this is true or not. In any event if you consider that the feet can have as many as 250,000 sweat glands it is easy to see how some of them could get "clogged" from constant friction and pressure and cause this condition to occur.

Any suspicious growth on any part of the body should be examined by a health care professional to determine if there is a possibility of malignancy. Porokeratosis are not malignant growths but should be looked at by a doctor to make sure.

The degree of discomfort a patient will experience will vary from person to person. In many people they are a non-issue but in others they can be very painful.

Factors that may exacerbate the pain include:

  • the number of lesions
  • their location on the foot
  • the type of shoe a patient wears, thin soled shoes are worse then cushioned shoes
  • the amount of walking a person does during the course of a day
  • the amount of, or lack of fat on the bottom of the foot.


TREATMENT OF POROKERATOSIS



For this reason there are various treatments ranging from absolutely nothing to surgical excision. In cases where there is pain during ambulation most podiatrists will attempt to curette (carve out) the lesion(s) from the surrounding skin.

porokeratosis on foot
  • In most cases, curetting the lesions can be done without anesthesia and is not a particularly painful procedure. This is usually what I do the first time a patient presents with this type of problem. Based on recurrence, if any, will determine further treatment. Many times curetting the lesion(s) will be the first and last treatment for these lesions. In other cases after a period of relief ranging from a couple of days to a few years the patient may return complaining of pain in the same area. If it has been a fairly long time since last treatment I may just go ahead and curette the lesion again.
  • Wearing a cushioned innersole, although it will not rid you of the porokeratosis may reduce the pressure on these lesions and make it more comfortable to walk.
  • In other instances if it has been a short period of time and the lesion has returned we need to look at other options. Other forms of treatment for porokeratosis plantaris include the use of keratolytic agents such as salicylic acid whose goal is "eat" away at the lesion by macerating the area. This can be done alone or in conjunction with curettement in an effort to extend the period of relief.
  • These lesions may also be injected. Cortisone injections are usually of no value but sclerosing agents such as 4% denatured alcohol can be effective. The problem here as you might imagine is that an injection directly into the bottom of the foot can be very painful. Usually it is necessary to give a nerve block at the level of the ankle which will numb the whole bottom of the foot, then the lesions may be injected directly locally with the sclerosing agent. It should be noted that sclerosing injection therapy may require upwards of three injections given over a three week period into each painful lesion. If there has not been significant improvement after three injections, this therapy should be discontinued.
  • Complete surgical excision of these lesions particularly those on the ball of the foot is not the treatment of choice. The problem here is that should there be an scarring as a result of the surgical procedure, the resulting scar may end up being more painful than the original growth.

Frequently Asked Questions

What is a porokeratosis?
A porokeratosis is a small, seed‑like keratotic lesion that forms on weight‑bearing areas of the foot, often feeling like a pebble in the shoe. These lesions are benign and are thought to result from plugged sweat glands or localized pressure and friction.
Why do porokeratoses hurt?
Pain depends on the number of lesions, their location, shoe type, walking habits, and the amount of natural fat padding under the foot. When pressure builds directly over a lesion, it can feel sharp and uncomfortable during standing or walking.
How are porokeratoses treated?
Most cases improve with simple curettement, where the lesion is carefully removed from the surrounding skin. Additional options include cushioned insoles, keratolytic agents like salicylic acid, or sclerosing injections for recurrent pain. Surgical excision is rarely recommended due to the risk of painful scarring.


REFERENCES

DermNet NZ

American Osteopathic College of Dermatology

National Institutes of Health

Questions I Have Answered From Visitors

Bubble under skin feet

by Veeree gongthong
Finland

Two months ago I found that there are some small bubbles under the skin of my feet. First 5 on the left and 2 on the right, but now 10 on the left and 4 on the right. They are not all together. In the middle of the sole is the biggest one. It is growing bigger under my skin and it does not bulge out. My surface skin looks fine. When I press on it, it hurts. When they are bigger it hurts more when I walk or stand for a long time.

I tried to use a needle on it but there is no juice coming out. I used plaster acid on it; only skin comes off but not the bubble. Still there are new ones coming too. How can I get it away?

Sometimes it does not hurt at all while I am walking, but some days it hurts so much. When I sit and rest and then move again it hurts less. How can I treat them? How can I prevent more from happening? I use acid for warts — will it help? In the picture I did not use acid yet, but because of the thick skin the acid does not go in.

Hi Veeree,

The two most common causes of multiple growths on the bottom of the feet would include warts or possibly porokeratosis.

Looking at just one lesion it appears to be more porokeratosis than wart. A porokeratosis is essentially a plugged sweat gland. Feet have 250,000 sweat glands; that is why they perspire so much. Excessive perspiration coupled with excessive pressure on some of these growths, along with the friction of walking on them, can cause one or more of them to “plug” up. Most people will relate a feeling of having a stone in their shoe all the time.

The pain is usually worse if a person is walking barefoot on a hard floor like tile or wood and will feel better walking on carpeting. Secondly, wearing a thin‑soled shoe like a dress shoe will cause more pain than wearing sneakers or any other type of shoe with a cushioned innersole.

This is a benign condition that is more of an annoyance than anything else.

Applying acid preparations purchased in a drug store is usually not effective simply because the acid is not strong enough to soften the growth, as the growth is being pushed into the skin. In most cases, having the growth curetted out (carved out) by a foot specialist can go a long way in relieving the pain. Treatment may be temporary or permanent. Some patients come in regularly to have these treated, while others find that one treatment solves the problem.

Wearing a cushioned innersole in your shoes may also help reduce symptoms but will not remove the actual porokeratosis.

Injections of 4% denatured alcohol may also help by sclerosing or deadening the lesion. Although I use 4% denatured alcohol injections for other foot problems, I have never actually used them on porokeratosis, simply because it can be a very painful injection going into the bottom of the foot and having to give multiple injections at multiple sites.

As I stated previously, they appear to be porokeratosis, but there is also the possibility that they are warts or even a remote chance they are something else.

You should not take my diagnosis as a true diagnosis. My best advice would be to see a local doctor in your area and have the lesions examined to confirm that they are nothing more than a benign growth. For that reason, and because I do not think you will be able to treat them yourself, a doctor’s appointment would be advisable.

Marc Mitnick DPM

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DISCLAIMER: The purpose of this site is purely informational in nature. It is not intended to diagnose, treat or cure any medical condition. This information is not a substitute for advice from a medical professional. Please consult your healthcare provider for accurate diagnosis and treatment. The information presented here may be subject to errors and omissions.


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