• Freiberg’s disease (Freiberg’s infraction/infarction) is a form of avascular necrosis affecting the metatarsal head—most commonly the second—caused by loss of blood supply to the bone. This leads to structural collapse, joint degeneration, and progressive pain in the ball of the foot.
• The condition typically begins during adolescence while the growth plate is still open, but symptoms often do not appear until the patient’s twenties or early thirties. It is far more common in females and is frequently aggravated by high heels or athletic activity.
• Repetitive stress to the metatarsal growth plate—rather than a single traumatic event—is believed to cause micro‑fractures that disrupt circulation. Over time this leads to flattening, fragmentation, and degeneration of the metatarsal head, visible on X‑ray.
• Symptoms include localized pain under the affected metatarsal, swelling, redness, and limited motion of the toe. Pain worsens with activity and may become chronic if the joint continues to deteriorate.
• Early treatment focuses on reducing stress to the bone through non‑weightbearing casting, stiff‑soled shoes, orthotics with metatarsal bars, and activity modification. Advanced cases may require surgery, including joint debridement, drilling to stimulate blood flow, partial metatarsal head resection, or dorsiflectory wedge osteotomy.
Freiberg's disease is also commonly known as Freiberg's infraction which means incomplete fracture or Freiberg's infarction which means necrosis or bone death due to obstruction of circulation.
In any event the condition is a result of avascular necrosis meaning the blood supply to the affected bone has been cut off causing the bone to undergo changes usually resulting in pain.
The disease can vary in severity and usually gets worse as time goes on. It usually begins in the second decade of life however may not manifest itself as pain until the patient reaches their early twenties. It is far more common in females then males.
As previously mentioned it is thought to be due to disruption of circulation to the head of the metatarsal bone, usually, but not always the second metatarsal bone. This disruption is thought to occur primarily from repetitive stress (such as running or wearing high heel shoes) and not necessarily one incidence of trauma. The trauma is to the growth plate of the bone (from which the bone grows in length over time), which is located at the distal (front) part of the bone nearer the toes.
The repeated stress to the growth plate of the bone causes micro fractures in the growth plate which eventually lead to a disruption of the blood supply to that area of the bone. It occurs while this growth plate is open (growth plates eventually close and there is no longer any further bone growth) which is during puberty. During this time period there is rarely pain.
While the growth plate is open, there is rarely pain, but the pain occurs later on, generally in females in their twenties and early thirties in response perhaps to wearing high heels or participating in athletics.
![]() Freiberg's disease x-ray |
Typically the patient complains of localized pain in the ball of the foot near the bone that is affected. The affected area may also be slightly red and swollen. There may also be limitation of motion of the affected toe. The pain is usually exacerbated by excessive activity and can worsen overall with time. In women, high heels may aggravate the pain.
An xray reveals the classic flattening of metatarsal head. There can also be fracture and fragmenting of the bone resulting in loose bodies of bone in the area causing further pain. All of this leads to degeneration of the joint between the metatarsal bone and toe.
The treatment of Freiberg's disease is dependent on the amount of bone destruction and the amount of pain the patient is experiencing.
In those situations where conservative measures have failed, surgery becomes a viable option. An MRI of the bone and joint should be performed prior to any surgical procedure in order to get a clear picture of the diseased joint, to see if there are any loose bone fragments in the joint and to check the overall bone stock or quality of the metatarsal bone.
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Surgical procedures:
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