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The response to the question below was authored by Marc Mitnick DPM
Isolated Itchy Spot on bottom of foot
i've had an isolated itchy spot on the right side under my foot, 2 inches below my second to last toe for a few years. I had this oval-ish spot the size of my thumb nail or a little larger removed and pathology found nothing. But, it relieved the sypmtom of sever itching that can't not be satisfied because it is so deep, I can feel the bally tissue. I used to take a fork to my foot to scratch it. Now it is back and I want it removed desperately but not sure what this is. I have wasted a ton of money on topicals etc; NOTHING works. My foot doc asked if I have back issues and I do. Is this related? why is this one little spot persistant and no where else or spread to the other foot? weird. thank you.
Sometimes lower back problems will cause neurological symptoms in the foot, but generally in a larger section of the foot.
My "guess" is you have a local nerve irritation at the point where it itches. Topicals will probably not help.
Ask your doctor about a cortisone shot directly in the area or even the possibility of denatured alcohol injections; they can be very helpful.
Marc Mitnick DPM